Carcharodontosauridae was named by Stromer (1931). It is not extant. Its type is Carcharodontosaurus. It was considered monophyletic by Benson et al. (2010), de Azevedo et al. (2013).

It was synonymized subjectively with Megalosaurinidae by Steel (1970).

It was assigned to Theropoda by Stromer (1931); to Theropoda by Martinelli and Forasiepi (2004); to Carnosauria by Currie and Carpenter (2000), Coria and Currie (2006); to Allosauroidea by Rauhut (1995), Sereno et al. (1996), Larsson (1996), Holtz (1996), Hutchinson and Padian (1997), Sereno (1997), Sereno (1998), Rauhut (2003), Holtz et al. (2004), Yates (2005), Novas et al. (2005), Brusatte and Sereno (2007), Brusatte and Sereno (2007), Sereno and Brusatte (2008), Brusatte et al. (2009), Candeiro et al. (2012), Canale et al. (2013), Novas et al. (2013), Hendrickx and Mateus (2014); to Carcharodontosauria by Benson et al. (2010), Carrano et al. (2012), de Azevedo et al. (2013), Sanz et al. (2014), Csiki-Sava et al. (2016), Carrano (2024); and to Carcharodontosauriformes by Kellermann et al. (2025).