Trachycardium was named by Mörch (1853) [Sepkoski's age data: T Than R Sepkoski's reference number: 705]. It is extant. Its type is Cardium isocardia.

It was reranked as Cardium (Trachycardium) by Aldrich (1911), Harris (1919), Oldroyd (1925), Vredenburg (1928), Loel and Corey (1932), Mukerjee (1939), Mansfield (1940), Pilsbry and Olsson (1941); it was reranked as Laevicardium (Trachycardium) by Grant and Gale (1931).

It was assigned to Laevicardium by Grant and Gale (1931); to Cardium by Aldrich (1911), Harris (1919), Oldroyd (1925), Vredenburg (1928), Loel and Corey (1932), Mukerjee (1939), Mansfield (1940), Pilsbry and Olsson (1941); to Cardiidae by Woodring (1938), Durham (1944), Marasti (1973), Frassinetti and Covacevich (1999); to Veneroida by Sepkoski (2002); and to Trachycardiinae by Olsson (1967), da Silva Forti (1969), Iqbal (1973), Adegoke (1977), Maxwell (1978), Vokes (1980), Woodring (1982), Dockery (1982), Coan et al. (2000), Moore (2003), Bouchet et al. (2010).